A) NORMAL DEVELOPMENT







B) ABNORMAL DEVELOPMENT

LEGEND

PSC     - Pluripotential stem cell
MSC    - Multipotential stem cell
IPSC    - Immunoreactive pluripotential stem cell
DSCE  - Directed stem cell of erythropoeisis
DSCG  - Directed stem cell of granulocytopoeisis
DSCM- Directed stem cell of monocytopoeisis
DSCT  - Directed stem cell of trombocytopoeisis

Erythropoesis

  • Proerythroblast (ProEryt) -> Basophylic erythroblast (BasoEryt) -> Polychromatic erythroblast (PolyEryt) -> Acidophylic erythroblast (AcEryt) -> Reticulocyte (Rtc) -> Erythrocyte (Eryt)
  • Promegaloblast (Pro meg) -> Basophylic megaloblast (Basomeg) -> Polychromatic megaloblast (Polymeg) -> Acidophylic megaloblast (Acmeg) -> Reticulocyte (Rtc) -> Megalocyte (Meg)

Granulocytopoeisis
Myeloblast (Myb) -> Promyelocyte (pMy) -> Myelocyte (My) - Neutrophils, Eosinophilis, Basophilis -> Metamyelocyte (mMy) - Neutrophils, Eosinophilis, Basophilis -> Non-segmented granulocyte (Stab) - Neutrophils, Eosinophilis, Basophilis -> Segmented granulocyte (SegGr) - Neutrophils (Neut), Eosinophilis (Eos), Basophilis (Bas)

Monocytopoeisis
Monoblast (Mon. b) -> Promonocyte (pMon) -> Monocyte (Mon) -> Free and fixed tissue macrophage (Macro)

Trombocytopoeisis
Megakaryoblasts (Megakarb) -> Promegakaryocyte (Promegkar) -> Megakaryocyte (Megakar) -> Trombocyte (Platelet) (Plt)

Immunocytopoeisis
T-system
Pre-T-cell (PreT) -> Lymphoblast (Lymbl) -> Prolymphocyte (Prolym) -> Thymocyte (Thym) -> T-lymphocyte (T-Lym)
B-system

Pre-B-cell (PreB) -> Lymphoblast (Lymbl) -> Prolymphocyte (Prolym) -> B-lymphocyte (B-lym) -> Plasmablast (Plasmabl) -> Proplasmocyte (Proplasm) -> Plasmocyte (Plasm) -> Plasma cell

Chronolab

Barcelona, Spain
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Quality Certification

The quality system implemented by Chronolab Systems is certified according standard ISO 9001-2008