Signaling substance | Colloidal gold | Organic fluorescence | Chemiluminescence | Quantum dot |
---|---|---|---|---|
Basic principle | Chromogenic reaction
| Organic light
| Chemiluminescence
| Physical material luminescence
|
Signal sensitivity
| Low | Medium | High | High |
Signal detection range
| Narrow | Medium | Wide | Wide |
Qualitative/quantitative product
| Qualitative/semi-quantitative
| Quantitative
| Quantitative
| Quantitative
|
Stability | Unstable | Unstable | Fast attenuation | Highly stable
|
Requirements on testing equipment
| Medium
| Medium
| Demanding | Medium |
Material cost per serving
| Low
| High | Relatively high
| Low |
01
Urease: the basis for judging whether HP exists
02
Cytotoxin (CagA): release inflammatory factors, causing inflammation
03
Vacuolar toxin (VacA): induces vacuolar degeneration of cells
Item | Traditional HP breath test | HP Typing Test Kit |
---|---|---|
Support typing
| NO
| YES |
Radiation
| YES | NO |
Prohibitions imposed
| Fasting, drug withdrawal, food, etc.
| NO |
Accuracy
| The rate of false positive/false negative is 10~20%
| ≥98.5%
|
Detection time
| 30min
| 15min
|
NO
| Automation and in batches
| Medium |
Barriers to entry
| Conventional
| Different instruments are suitable for various scenarios
|
Cost
| Conventional
| Low-cost
|
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